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Discover Supplement-Drug Interactions

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Last Updated: 5 months ago

Possible Interaction: Arginine and Trazodone

supplement:

Arginine

Research Papers that Mention the Interaction

Systemic L-arginine (50 mg/kg) pretreatment with sub-effective dose of sertraline (10 mg/kg), venlafaxine (10 mg/kg), imipramine (10 mg/kg) and trazodone (10 mg/kg) for 14 days significantly attenuated their protective effect.
Journal of psychopharmacology  •  2011  |  View Paper
L-arginine , pretreatment with trazodone or citalopram significantly reversed their protective effects.
Indian journal of experimental biology  •  2010  |  View Paper
However, L-arginine (100 mg/kg) pretreatment reversed the protective effect of trazodone (5 mg/kg) (p<0.05).
In addition, L-arginine (100 mg/kg) and L-NAME (5 mg/kg) were administered 15 min before administration of trazodone (5 mg/kg).
Pharmacological reports : PR  •  2008  |  View Paper