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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
Research Papers that Mention the Interaction
“The arginine vasopressin V2 receptor antagonists OPC-31260 and tolvaptan inhibit the development of polycystic kidney disease in cpk mice and in three animal orthologs to human autosomal recessive polycystic kidney disease (PCK rat), autosomal dominant polycystic kidney disease (Pkd2-/WS25 mice), and nephronophthisis(pcy mouse).”
Role of vasopressin antagonists.“The arginine vasopressin V2 receptor antagonists OPC-31260 and tolvaptan inhibit the development of polycystic kidney disease in cpk mice and in three animal orthologs to human autosomal recessive polycystic kidney disease (PCK rat), autosomal dominant polycystic kidney disease (Pkd2/WS25 mice), and nephronophthisis (pcy mouse).”
“ Tolvaptan attenuated the MI-induced mRNA expressions of atrial and brain natriuretic peptides, monocyte chemotactic protein-1, transforming growth factor-&bgr;1, arginine vasopressin V1a receptor, and endothelin-1 in the marginal infarct region.”
Tolvaptan Improves Left Ventricular Dysfunction after Myocardial Infarction in Rats“ Tolvaptan inhibits the binding of arginine vasopressin to the V2 receptors on the collecting ducts of the kidneys resulting in aquaresis, the electrolytes sparing excretion of water.”
Tolvaptan, hyponatremia, and heart failure
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