Possible Interaction: Arginine and Threonine

“Age at enrollment R = -0.26; p < 0.001), baseline HR before the CB-A (R = -0.32; p < 0.001), nadir temperature in each right pulmonary vein (R = -0.11, p = 0.022; R = -0.16; p = 0.001) were significantly associated with the ∆HR.”

“ L-Arg supplementation increased the activity of inducible nitric oxide synthase (iNOS), the rate of protein synthesis, and the phosphorylation of mTOR ( Thr 2446) and p70S6K (Thr 389).”

“These results indicate that L-Arg stimulates protein synthesis via the activation of the mTOR ( Thr 2446)/p70S6K signaling pathway in an NO-dependent manner.”

“By contrast, in CSF, serine, threonine , and tyrosine decreased (-20, -24, and -31%, respectively) after R feeding.”

“Net utilization of lysine, threonine , isoleucine, leucine, glycine and alanine by jejunal or ileal mixed bacteria decreased (P < 0.05) with the addition of arginine.”

“With the addition of arginine , net utilization of threonine , glycine, phenylalanine and branched-chain AA increased (P < 0.05) in Streptococcus sp. and Klebsiella sp., but decreased in E. coli.”

“The absorption of serine and threonine stimulated the absorption of arginine.”

“Additionally, ΔHR decreased in both L-Arg and SNP, but was only significant in L-Arg.”

“Substitution of a highly conserved threonine for alanine or arginine resulted in a loss of EsaB activity and destabilisation of the protein.”

“More importantly, they were found to have a profound effect on the luminescence responses to arginine compared with glutamic acid, histidine, tryptophan, threonine , tyrosine and phenylalanine in aqueous environment.”

“One-to-one molar ratios of arginine heated with threonine , valine, cystine, cysteine or tryptophan produced reaction products that gave 1200-3200 revertants/mmol in Salmonella strain TA98 with metabolic activation.”

“All other amino acids with the exception of histidine, arginine , asparagine, and hydroxyproline inhibited threonine uptake.”