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“The combination of L-arginine (20 and 40 mg/kg) with the highest dose of theophylline potentiated the hypothermic effect induced by the latter drug, while L-arginine by itself did not alter body temperature.”
European journal of pharmacology • 2002 | View Paper
“In vivo, compared with control rabbits, both L-NAME and L-arginine increased theophylline plasma concentrations secondary to a reduction in theophylline systemic clearance by 46% and 42% (p < 0.05), respectively.”
Drug metabolism and disposition: the biological fate of chemicals • 1997 | View Paper
“Using an in vitro assay we investigated the capacity of spleen lymphocytes from NOD mice to inhibit the insulin secretion of normal islet cells after stimulation by theophylline plus arginine.”
Clinical and experimental immunology • 1988 | View Paper
“N6,O2‐Dibutyryl adenosine 3′:5′‐cyclic monophosphoric acid (But2c‐AMP) (10−4 M) and theophilline (10−3 M) inhibit arginine uptake and the initiation of DNA synthesis by serum.”