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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“In the presence of l-arginine , the inhibitory effect of tempol on NHE activity was reduced to -19 ± 6% (n = 6; P < 0.03).”
Endogenous flow-induced nitric oxide reduces superoxide-stimulated Na/H exchange activity via PKG in thick ascending limbs.“However, … of L-arginine … TPL was significantly improved, e.g. the Work Index=(left ventricular developed pressure x heart rate) recovered to 92+/-1.6% (L-arginine …+/-2.9% (L-arginine) and 53.3+/-4.3% (TPL) of the pre-ischemic value; mean+/-SEM, N=10, P<0.001.”
“The combined … of L-arginine … TPL reduces the negative effects of NO by either inhibiting the production of ONOO(-) or through reaction with CO(3)z.rad;(-) and *NO(2) radicals formed during the decomposition of peroxynitrite in the presence of bicarbonate, thus promoting cardioprotection following post-ischemic reperfusion.”
“At all concentrations of L-Arg tested (50, 100, 250, 500, and 750 micromol/L), further addition of Tempol to the bath significantly increased NO release by THALs.”
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