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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Arginine
drug:
Tarenflurbil
Research Papers that Mention the Interaction
“Modest enantioselectivity in clearance (CL S/R: young, 0.… responsible for the apparent elimination half-life of (S)-flurbiprofen being significantly greater ( p<0.01) than that of … groups (young, S: 5.2 ± 0.7 versus R : 4.5 ± 0.6 h; elderly, … R: 7.1 ± 1.0 h).”
Disposition of flurbiprofen in man: influence of stereochemistry and age“In comparison to S (+)-flurbiprofen, R (−)-flurbiprofen concentration was significantly higher in plasma at all time points (p < 0.05) except at 30 or 40 min, and lower in CSF at all time points (p < 0.05) except at 10, 15 and 40 min.”
The Comparison of Plasma and Cerebrospinal Fluid R(−)- and S(+)-Flurbiprofen Concentration After Intravenous Injection of Flurbiprofen Axetil in Human Subjects
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