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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Arginine
drug:
Substance P
Research Papers that Mention the Interaction
“In addition, we measured forearm blood flow while infusing substance P before and during infusion of L-arginine (10 mg/min, simultaneously), or before and 1 h after oral administration of indomethacin (75 mg).”
Role of nitric oxide towards vasodilator effects of substance P and ATP in human forearm vessels.“We found that SP stimulation led to an increased rate of collagen remodeling mediated via the neurokinin‐1 receptor ( NK‐1 R ), the preferred cell receptor for SP.”
“In transplant recipients, bi-coronary co-infusion of substance P and of L-arginine , the substrate for NO production, potentiated the fall in LV filling pressures.”
“ L-Arginine analogs (10(-4) to 10(-2) mol/L) inhibited the effect of substance P (p < 0.02 at the higher concentration).”
“A23187, bradykinin or substance P increased NO synthesis from L-arginine by EC in the presence or absence of L-glutamine.”
L-glutamine inhibits nitric oxide synthesis in bovine venular endothelial cells.“Pretreatment with L-arginine prevented the potentiated responses in the pulp and those induced by the lower doses of substance P in the oral mucosa.”
“Pretreatment with an intracisternal injection of 10 ¨mol of NG-monomethyl L-arginine suppressed the vasodilator effect of vasopressin and substance P , whereas it did not affect the response to vasoactive intestinal peptide.”
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