Possible Interaction: Arginine and Somatropin

“Compared with saline infusion, arginine induced higher HGH increases but glucagon and epinephrine did not.”

“Fasting serum concentrations of alanine, glycine, arginine , and tryptophan were also significantly elevated (P less than .01) with hGH treatment; ornithine, tyrosine, lysine, methionine, and phenylalanine showed lesser elevations (P less than 0.5), whereas threonine decreased significantly (P less than 0.01).”

“Patients receiving an arginine infusion also demonstrated diminished HGH response following injury.”

“Further by maintaining high levels of hGH either by provocative stimuli or by hGH infusion, the typical hypothalamo-pituitary response to exercise, arginine and hypoglycaemia is prevented or lessened.”

“Intravenous infusion of arginine caused a significant increase in plasma hGH , with peak hGH levels of 20.6 ± 4.9 ng/ml (mean ± sem).”

“In controls as well as HGH deficient dwarfs, the mean maximal insulin responses to arginine and glucose were increased two- to fourfold by HGH treatment (5 nig.”

“These progressive changes in the response of HGH to arginine stimulation during the three trimesters of pregnancy suggest that the dynamics are related to physiologic alterations requiring months to become fully manifest.”

“There is, in addition, a rise in plasma HGH concentration after arginine , a response which is quantitatively greater in the female than in the male (Merimee, Lillicrap & Rabinowitz, 1965; Merimee, Burgess & Rabinowitz, 1966).”