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“Isobolographic analysis revealed an additive effect for scopolamine and l-Arginine or l-NAME.ConclusionData suggests that NO agents could positively impact the therapeutic profile of scopolamine, because they might be useful for inducing antidepressant-like effect associated to scopolamine.”
“Joint administration of sub-effective dose of scopolamine (0.01 mg/kg) with a low dose of l-Arginine (25 mg/kg) or l-NAME (1 mg/kg) induced a profound antidepressant-like effect in the FST.”
“Solanaceae) roots (RB-1), whereas, other precursors (ornithine, arginine , and tropine) increased the content of scopolamine only slightly or not at all.”