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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arginine
drug:
Paroxetine
Research Papers that Mention the Interaction
“ Paroxetine coadministration significantly increased S and R metoprolol area under the plasma concentration‐time curve from time 0 to the 24‐hour blood draw (AUC0‐24h) by 4‐ and 5‐fold, respectively for IR, and 3‐ and 4‐fold, respectively, for ER.”
Influence of Metoprolol Dosage Release Formulation on the Pharmacokinetic Drug Interaction With Paroxetine“Area under the concentration-time curve (AUC) increased significantly with paroxetine coadministration, approximately 2.5-fold and 1.9-fold for the R and S enantiomers, respectively.”
“ l-arginine prevented the inhibitory effects of paroxetine (105.5 and 115.3%) and partially prevented duloxetine-induced reduction of GVRs but had no effect on the inhibition of GVRs induced by venlafaxine.”
Mechanisms for the Inhibition of Genital Vascular Responses by Antidepressants in a Female Rabbit Model
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