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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arginine
drug:
Nitroglycerin
Research Papers that Mention the Interaction
“The antral motor activity, calculated as the motility index (number of … mmHg/min) significantly decreased in both test series, i.e., after GTN from 375.5 +/- 185.1 (control) to 104.… +/- 55.7 (P < 0.01) and after L-arginine from 401 +/- 76 (control) to … +/- 57 (P < 0.05).”
Effects of nitric oxide on antral motility and gastric emptying in humans.“Auditory-perceptual analysis indicated greater compromising of voice parameters for NG , compared to CG: G (79 versus 24), R (53 versus 3), B (67 versus 23) and S (35 versus 1).”
“Additionally, R compared to control significantly reduced weekly angina frequency and weekly nitroglycerin consumption.”
“Other electrocardiographic estimates of the extent of myocardial necrosis, including the percent reduction in R wave amplitude and the relative changes in R and Q wave amplitude, also were significantly less in those receiving nitroglycerin.”
“Addition of the nitric oxide precursor, L-arginine , did not affect acetylcholine relaxation, yet surprisingly had a differential effect in response to nitroglycerin.”
“Although L-arginine , alone, did not cause any vasodilator response in coronary microvessels, it was able to potentiate nitroglycerin relaxations at control (no L-arginine: 25 +/- 6% vs. L-arginine: 135 +/- 66%).”
Altered vasodilator response of coronary microvasculature in pacing-induced congestive heart failure.“ NTG caused an increase in CBF in the LAD averaging 21 +/- 10 mL/min before CSA, 13 +/- 11 mL/min after CSA, and 14 +/- 7 after administration of L-arginine (P = .009).”
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