Possible Interaction: Arginine and Nitroarginine

“N omega-nitro-L-arginine (18 mM) antagonized the increase in AMC induced by L-arginine in preparations indirectly stimulated, and a similar effect was obtained against the depression induced by L-arginine in directly stimulated muscle preparations.”

“The effect of NG-nitro-L-arginine was prevented by pre-exposure of hypothalami to L-arginine (1 mM).”

“The inhibitory effect of L-NNA was reversed by L-arginine , a substrate for NO synthase, but not by D-arginine.”

“The inhibition produced by L-NNA was reversed by either L-arginine or L-citrulline.”

“L‐Arginine but not D‐arginine overcame the blockade elicited by nitro‐L‐arginine.”

“Subsequent administration of NAA (20 mg/kg) rapidly and completely reversed the hypotension and increased systemic vascular resistance; these effects of NAA were reversed by L-arginine.”

“The effects of NAA were then reversed by the administration of L-arginine.”

“synthesis by NAA is reversed by excess L-arginine.”

“ l-NNA concentration-dependently inhibited the relaxation in response to EFS in the human IAS, and this inhibitory effect in the IAS was reversed by l-arginine.”

“ L-NNA concentration dependently inhibited the relaxation in response to EFS in the human pylorus, and this inhibitory effect in the pylorus was reversed by L-arginine.”

“ L-NNA caused an increase in tone (5.97 +/- 0.84 mN) and frequency, L-Arginine significantly reversed this effect.”

“ L-Arginine (10-(4) M) inhibited the blocking effect of L-NNA.”