supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Moreover, GH levels stimulated by arginine , sleep, exercise, L-dopa and hypoglycaemia are modestly or not at all inhibited by naloxone (Morley 1981; Grossman & Rees, 1983), suggesting that opioids are not important modulators of GH secretion in man.”
Inhibition of growth hormone release by naloxone in adult Tourette's syndrome subjects.“Both L-ARG and SIN-1 caused dose-related antinociceptive effects that were blocked by naloxone and norbinaltorphimine.”
Dynorphin-mediated antinociceptive effects of l-arginine and SIN-1 (an NO donor) in mice“Fourth ventricular administration of L-arginine had no effect on the response to graded caval occlusion but was able to reverse the phase II blocking action of N-nitro-L-arginine methyl ester and naloxone.”
“The antiamnesic effect of Morphine and Arg , but not that of Ala or NMDA was blocked by naloxone.”
“Dipeptide Lys-Arg and free arginine also possess a marked analgetic activity which is abolished by naloxone.”
“This antinociceptive activity was fully antagonized by naloxone (a nonselective opioid antagonist) but was partially reversed by l-arginine (l-arg; a nitric oxide [NO] precursor), Nω-nitro-l-arginine methyl ester hydrochloride (l-NAME; an NO synthase inhibitor), or their combinations thereof.”
Methanolic Extract of Clinacanthus nutans Exerts Antinociceptive Activity via the Opioid/Nitric Oxide-Mediated, but cGMP-Independent, Pathways
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback