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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Objective We investigated whether the … oxide (NO) precursor, l-arginine , can prevent the antidepressant-like … of the fast-acting antidepressant, ketamine , in a genetic rat model of depression, and/or induce changes in the glutamate (Glu)/N-methyl-d-aspartate receptor (NMDAR)/NO/cyclic guanosine monophosphate (cGMP) signalling pathway.”
“Results l-Arginine pre-treatment prevented the antidepressant-like effect of ketamine in the FST, as well as a ketamine-induced increase in cGMP levels in the frontal cortex and hippocampus of FSL rats.”
Nitric oxide involvement in the antidepressant-like effect of ketamine in the Flinders sensitive line rat model of depression“The antidepressant effects of ketamine were prevented by pre-treatment with l-arginine (750 mg/kg).”
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