supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Arginine
drug:
Interferons
Research Papers that Mention the Interaction
“We found that L-arginine significantly elevated the number of splenic CD8+ T-cells, the level of serum interferon-γ , and CD8+ T-cell infiltration.”
Combination therapy with L-arginine and α-PD-L1 antibody boosts immune response against osteosarcoma in immunocompetent mice“Conclusions Interferon-&ggr ; aggravated L-arginine –induced AP in Sprague-Dawley rats and led to intracellular trypsinogen activation and inflammatory response.”
Interferon-&ggr; Aggravated L-Arginine–Induced Acute Pancreatitis in Sprague-Dawley Rats and Its Possible Mechanism: Trypsinogen Activation and Autophagy Up-regulation“ Interferon tau and progesterone stimulate transport of amino acids in histotroph, particularly arginine.”
“In addition, Arg elevated the levels of serum interleukin-2 and interferon-γ (P < 0.05) on day 28, and mitigated the decrease of serum interferon-γ level on day 21 (P < 0.05).”
“Following a 24-h exposure to IL-1β and IFN, arginine uptake increases (V = 167 pmol/2 × 105 cells/min) and a second low-affinity L-arginine transporter activity appears (K = 1.2 mM).”
“ Arginine methylation of TLR4 on R812 or PRMT2 enhanced interferon-β (IFN-β) production.”
Arginine methylation by PRMT2 promotes IFN-β production through TLR4/IRF3 signaling pathway.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback