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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Arginine
drug:
Hypochlorite
Research Papers that Mention the Interaction
“These results suggest that HOCl reacts with l-Arg to form chlorinated products that act as nitric-oxide synthase inhibitors.”
“Using spectrophotometric techniques, we found that HOCl and l-Arg react rapidly (k= 7.1 × 105 m − 1s− 1) to form two major products that were identified by mass spectrometry as monochlorinated and dichlorinated adducts of l-Arg.”
l-Arginine Chlorination Products Inhibit Endothelial Nitric Oxide Production*“These data suggest that HOCl induces endothelial dysfunction via modification of L-arginine.”
Endothelial dysfunction is induced by proinflammatory oxidant hypochlorous acid.
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