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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Arginine and Hesperidin





Research Papers that Mention the Interaction

l-arginine and l-NAME attenuated and potentiated the effect of a lower dose of hesperidin , respectively.
International journal of stroke : official journal of the International Stroke Society  •  2009  |  View Paper
Pretreatment with l-arginine (a nitric oxide (NO) precursor), sildenafil (a phosphodiesterase 5 inhibitor) or S-nitroso-N-acetyl-penicillamine (a NO donor) significantly reversed the reduction in immobility time elicited by acute treatment with hesperidin (0.3mg/kg) in the TST.
Brain Research Bulletin  •  2014  |  View Paper
Further, treatment with l-arginine (100 mg/kg) or l-NAME (10 mg/kg) in combination with hesperidin significantly modulated the protective effect of hesperidin which was significant as compared to their effects per se in PTZ-treated animals.
Epilepsy & Behavior  •  2013  |  View Paper
L-arginine (100 mg/kg) or L-NAME (10 mg/kg) pretreatment with lower dose of hesperidin (50 mg/kg) significantly reversed or potentiated its protective effect, respectively which was significant as compared to hesperidin (50 mg/kg).
Indian journal of experimental biology  •  2011  |  View Paper
L-arginine (100 mg/kg) pretreatment attenuated the protective effect of the lower dose of hesperidin on memory behavior, biochemical and mitochondrial dysfunction compared with hesperidin alone.
Pharmacological reports : PR  •  2010  |  View Paper
L-Arginine (50 mg/kg) pretreatment with lower dose of hesperidin (50 mg/kg) and naringin (50 mg/kg) significantly attenuated the protective effect of hesperidin and naringin respectively.
Behavioural Brain Research  •  2010  |  View Paper