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Possible Interaction: Arginine and Guanidines

supplement:

Arginine

supplement:

Guanidines

Research Papers that Mention the Interaction

Arginine , an essential amino acid found in many interaction interfaces, is capable of an impressive range of interactions via its guanidinium group.
Chemphyschem : a European journal of chemical physics and physical chemistry  •  2019  |  View Paper
This is due to the ability of the orientationally amphiphilic guanidinium cations to disrupt various secondary structural motifs of proteins by pairing promiscuously with both hydrophobic and hydrophilic groups, including guanidinium-containing side chains of arginines.
Accounts of chemical research  •  2018  |  View Paper
Recent experiments suggest that the dissociation constant for arginine is much higher than 12.5, which explains why the arginine guanidinium group retains its positive charge under all physiological conditions.
Chemphyschem : a European journal of chemical physics and physical chemistry  •  2017  |  View Paper
Therefore, the group interaction involved by guanidine has changed the fluorescence properties of L-arginine aggregates in LAP solution, indicating that the specific interaction between phosphate and guanidine exists in LAP molecule.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy  •  2015  |  View Paper
The guanidinium and carboxylate groups of substrates are tightly bound, which explains activity of PPAD against arginines at C-termini but not within peptides.
Scientific reports  •  2015  |  View Paper
The inhibitory nature of guanidine and arginine toward the esterase activity is reported.
The Biochemical journal  •  1973  |  View Paper
Interestingly, N-acetylated arginine, which lacks the α-amino group, showed a weaker suppressive effect on protein aggregation than Arg, even at neutral pH. These results indicate that both positively charged α-amino group and guanidinium group play important roles in suppressing heat-induced protein aggregation by Arg.
International journal of biological macromolecules  •  2016  |  View Paper
The concentration of L-arginine (0.05 nmol/mg tissue) is significantly lower than the other guanidines.
Biochemical and biophysical research communications  •  1992  |  View Paper
A similar inhibition of macrophage leishmanicidal activity and of NO2- release was observed using media treated with arginase (which converts L-arg to urea and ornithine), or supplemented with NG-monomethyl-L-arg or guanidine (which inhibit the conversion of L-arg to nitrogen oxidation products).
Journal of leukocyte biology  •  1991  |  View Paper