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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Arginine attenuated and prolonged the glucose rise when it was ingested with glucose.”
Oral arginine does not stimulate an increase in insulin concentration but delays glucose disposal.“In group 2, L-arginine normalized basal cGMP levels and significantly increased forearm blood flow by 36% and glucose disposal during the clamp by 34% whereas it decreased systolic blood pressure and endogenous glucose production by 14 and 29%, respectively.”
“These results suggest that the addition of arginine to a CHO supplement reduces the rate of CHO oxidation postexercise and therefore may increase the availability of glucose for muscle glycogen storage during recovery.”
“After leucine infusion, the decline of glucose continued, but stabilized or reversed with arginine such that by the end of the infusions, glucose levels were 6.63 +/- 0.69 mmol/L for leucine and 7.62 +/- 0.67 for arginine (P < .02).”
“The close interrelationship between arginine and glucose regarding insulin secretion was further illustrated by the finding that the insulin response to intravenous glucose infusion was markedly enhanced by the prior administration of arginine.”
“These findings indicate that synergism between arginine and glucose appears only when glucose itself is able to elicit insulin release.”
“In conclusion, glucose promotes iron-mediated oxidation of apoB- 100 proline and arginine residues via a superoxide-dependent mechanism, thus rendering the LDL particles more atherogenic.”
“After overnight culture, isolated islets, from five of seven batches, had poor insulin response to an in vitro glucose challenge that was only partially increased by additional challenge with arginine.”
“Insulin secretion/insulin resistance (disposition) index declined by 60% (2nd clamp step) and by 62% following arginine (both p<0.005) following 72 hour glucose infusion.”
“At baseline glucose, L-arginine increased total and active GLP-1 and glucagon concentrations in all GT populations (all P < 0.05).”
“In one such motif, called glucosepane, the side chains of lysine and arginine form a condensed cross-link through a reaction sequence with glucose.”
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