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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arginine
drug:
Gemcitabine
Research Papers that Mention the Interaction
“…,arginine … gemcitabine on PANC-1 cells via multiple mechanisms including induction of cell cycle arrest in the S phase, upregulation of the expression of caspase-3 … survival pathway by blocking NF-κB p65 signaling via suppressing the nuclear translocation and phosphorylation (serine 536) of NF-κB p65 in vitro.”
Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-κB signaling“On the other hand the coupling of Gem with peptides containing block sequence of arginine (R5W3R4) and some alternating sequences (i.e. [RW]6 and [RW]3) exhibited improved antitumor activity of the drug.”
Cellular uptake and anti-tumor activity of gemcitabine conjugated with new amphiphilic cell penetrating peptides
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