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Last Updated: 3 years ago

Possible Interaction: Arginine and Diclofenac

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supplement:

Arginine

drug:

Diclofenac

Research Papers that Mention the Interaction

“Pretreatment with L-arginine , the natural substrate for the nitric oxide synthetase, antagonized diclofenac , and S(+)-ibuprofen-induced suppression of the biting, scratching, and licking response evoked by intrathecal N-methyl-D-aspartate.”

Nonsteroidal antiinflammatory drug modulation of behavioral responses to intrathecal N-methyl-D-aspartate, but not to substance P and amino-methyl-isoxazole-propionic acid in the rat.

Journal of clinical pharmacology • 1996 | View Paper

“The antinociceptive effects of diclofenac , ibuprofen and paracetamol were reversed by L-arginine , but not by D-arginine.”

Central antinociceptive effects of non-steroidal anti-inflammatory drugs and paracetamol. Experimental studies in the rat.

Acta anaesthesiologica Scandinavica. Supplementum • 1995 | View Paper

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