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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Diazoxide treatment increased by 5.5-fold the insulin response to 10 mmol/L arginine , by 4.1-fold the graft insulin content, and by 2.3-fold the preproinsulin mRNA versus nontreated diabetic controls.”
Treatment with diazoxide causes prolonged improvement of beta-cell function in rat islets transplanted to a diabetic environment.“ Diazoxide given at this time partially blocked the fall in glucose-induced insulin secretion and totally prevented that with arginine.”
“The insulin secretion rate in response to 10 mmol/l arginine was also dose-dependently suppressed by concomitant infusion of diazoxide.”
“Previous diazoxide treatment enhanced the response not only to glucose but also to 2.5 mM barium or 10 mM arginine.”
“ Diazoxide also inhibited the insulinotropic effect of leucine and related substances (ketoisocaproate and BCH), but not that of potassium or of arginine and other cationic amino acids.”
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