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Last Updated: 2 years ago

Possible Interaction: Arginine and Dexamethasone

supplement:

Arginine

Research Papers that Mention the Interaction

The demonstration that L-arginine and vitamin C can partially offset the effects of dexamethasone on microvascular arterioles suggests the potential clinical usefulness of these agents for the reduction of glucocorticoid-induced hypertension.
American journal of physiology. Heart and circulatory physiology  •  2005  |  View Paper
Patients with DM had increased ammonia, citrulline, urea, uric acid, and ornithine, mainly in the RBCs, whereas the level of arginine was significantly lower in men with type 2 DM.
PloS one  •  2019  |  View Paper
Dexamethasone treatment (6 mg/day for 60 h) markedly enhanced the insulin response to arginine in subjects with high response (+99% 0–30 min) but failed to affect the subjects with low response (+4% 0–30 min).
Diabetologia  •  2004  |  View Paper
Furthermore, in high but not in low insulin sensitivity, dexamethasone reduced the glucagon response to arginine (p = 0.043).
Diabetologia  •  1999  |  View Paper
In HuH-7.MCAT-1 cells l-arginine uptake was significantly up-regulated by norepinephrine and dexamethasone , and hepatocyte growth factor also increased l-arginine uptake along with cellular DNA synthesis.
The Journal of Biological Chemistry  •  1998  |  View Paper
In all cases, there was a linear log-log correlation between R and DM.
The Tohoku journal of experimental medicine  •  1994  |  View Paper
Nitrite accumulation was accompanied by cell damage, which was increased by L-arginine and inhibited by NG-monomethyl-L-arginine (L-NMMA) and dexamethasone.
Biochimica et biophysica acta  •  1991  |  View Paper
Interestingly, the insulin release during arginine load was significantly decreased in NT and IT as well as in DM patients.
Neurology  •  1988  |  View Paper
Dexamethasone not only suppressed by 50% the spontaneous Fc epsilon R expression on U937 cells but also completely inhibited the enhancement of their Fc epsilon R expression on U937 cells induced by PMA, IFN-gamma or H107.
Clinical and experimental immunology  •  1988  |  View Paper
Dexamethasone administered to healthy subjects in a daily dose of 3 mg over a four day period caused significant increases in alanine and methionine levels (26%) as well as a rise in arginine.
Diabete & metabolisme  •  1982  |  View Paper
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