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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arginine
drug:
Dantrolene
Research Papers that Mention the Interaction
“Implications: In this study, we demonstrated that dantrolene , a drug that reduces the intracellular Ca2+ level, can inhibit L-arginine availability and inducible nitric oxide synthase activity in macrophages.”
“We conclude that the mechanisms by which dantrolene attenuated NO synthesis may be associated with the inhibition of availability of L-arginine by reducing the affinity for L-arginine, accompanied by a parallel decrease of the activity of iNOS.”
The Inhibition by Dantrolene of L-Arginine Transport and Nitric Oxide Synthase in Rat Alveolar Macrophages
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