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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Arginine and Dantrolene

supplement:

Arginine

Research Papers that Mention the Interaction

Implications: In this study, we demonstrated that dantrolene , a drug that reduces the intracellular Ca2+ level, can inhibit L-arginine availability and inducible nitric oxide synthase activity in macrophages.
We conclude that the mechanisms by which dantrolene attenuated NO synthesis may be associated with the inhibition of availability of L-arginine by reducing the affinity for L-arginine, accompanied by a parallel decrease of the activity of iNOS.
Anesthesia and analgesia  •  1998  |  View Paper