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Last Updated: 2 years ago

Possible Interaction: Arginine and D-Arginine

supplement:

Arginine

supplement:

D-Arginine

Research Papers that Mention the Interaction

Systemic infusion of 10 g of L-arginine (n = 5) or D-arginine (n = 3) increased plasma concentration of arginine approximately 20-fold without altering supine or erect haemodynamics.
Clinical science  •  1995  |  View Paper
Interestingly, the effect of l-arginine was stronger than that of d-arginine at various concentrations, and the effect of other cationic amino acids such as lysine and histidine was relatively lower than that of arginine.
International journal of pharmaceutics  •  2017  |  View Paper
Nevertheless, the L-Arg concentration decreased after D-Arg administration with time compared to the case post L-Arg administration.
The Journal of veterinary medical science  •  2020  |  View Paper
In conclusion, both l- and d-Arg significantly affected enzymes and metabolites in several pathways that use arginine as a substrate and further studies with different doses and treatment durations are planned to establish their safety or adverse effects to guide their use as oral supplements.
British Journal of Nutrition  •  2019  |  View Paper
L-NAME and D-Arg did not alter JCl; in contrast, addition of 0.5 mM L-Arg decreased JCl by 40.2 +/- 10.4% from control.
The American journal of physiology  •  1999  |  View Paper
This biocompatibility diminishes when L-arginine is substituted with D-arginine or when the biodegradable ester linker changes to a biostable ether linker.
Advanced functional materials  •  2011  |  View Paper
The basic amino acids ornithine, lysine, and D-arginine inhibited arginine transport.
The Journal of biological chemistry  •  1992  |  View Paper
In contrast, arginine transport was inhibited 43% when D-arginine was present at a concentration 16-fold higher than that of L-arginine.
The Journal of biological chemistry  •  1986  |  View Paper
L-Argininamide and D-arginine gave about the same inhibition as L-arginine.
European journal of biochemistry  •  1979  |  View Paper