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Last Updated: 4 years ago

Possible Interaction: Arginine and Cocaine

supplement:

Arginine

supplement:

Cocaine

Research Papers that Mention the Interaction

Significant inhibition of arginine transport was detected with nicotine (P =.007), cocaine (P =.01), and their combination (P =.01), whereas phenylalanine (P =.03, P =.04) and valine (P =.03, P =.04) transport was affected by cocaine and the combination of cocaine and nicotine, respectively.
The Journal of pharmacology and experimental therapeutics  •  2000  |  View Paper
Surprisingly, we found that previous cocaine exposure enhanced R –O associations in DLS.
The Journal of Neuroscience  •  2017  |  View Paper
NOS inhibitors (S‐ethylisothiourea and S‐isopropylisothiourea), a NO scavenger (2‐(4‐carboxyphenyl)‐4,4,5,5‐tetramethylimidazoline‐1‐oxyl‐3‐oxide), DA, and cocaine blocked the L‐Arg effect.
Synapse  •  2004  |  View Paper
In conclusion, these data demonstrate that cocaine stimulates the conversion of L-arginine to NO in the brain of rat and this is affected by concomitant exposure to acoustic stimulation.
Neuroscience Letters  •  1999  |  View Paper
Cocaine not only increases brain dopamine levels but also activates the sigma1 receptor ( σ1 R ) that in turn regulates orexigenic receptor function.
Addiction biology  •  2021  |  View Paper