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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arginine
drug:
Chloroquine
Research Papers that Mention the Interaction
“We propose that arginine deprivation-based combinational treatments that include autophagy inhibitors (e.g., chloroquine ) may produce a stronger anticancer effect as a second line therapy for a subset of chemoresistant ovarian cancers.”
Single Amino Acid Arginine Deprivation Triggers Prosurvival Autophagic Response in Ovarian Carcinoma SKOV3“The results showed a peak of pruritus in R + subjects between 6 to 30 h after taking the chloroquine tablets , consistent with the report of Ajayi et al. [4].”
“Acute single injection of a sub-effective dose of l-arginine (NO precursor, 60 mg/kg) with a sub-effective dose of chloroquine 2.5mg/kg increased the seizure threshold but administration of L-arginine 60 mg/kg with chloroquine 10mg/kg decreased the seizure threshold.”
Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice“Arginine-stimulated insulin response in vivo displayed a complex pattern; it was increased when arginine was injected together with chloroquine but decreased at 24 hrs after chloroquine administration.”
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