Possible Interaction: Arginine and Caseins

“In conclusion, arginine could relieve the inflammatory reaction induced by LPS and enhance the concentration of β-casein and the total casein in bovine mammary epithelial cells.”

“Addition of enough arginine to casein to lower its L/A to 1 reduces its atherogenicity; adding enough lysine to soy isolate to raise its L/A to 2 enhances atherogenicity.”

“Methionine (Met) and arginine Arg ) regulate casein protein abundance through alterations in activity of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway.”

“The results indicated that ARG inhibited fibril formation by reduced and carboxymethylated κ-casein (RCMκ-CN), and there was interaction between ARG and RCMκ-CN, proved by the observation of enhancement in RLS intensity attributed to the formation of RCMκ-CN-ARG complex.”

“Taken together, Arg appears to play an important role in the transcriptional regulation of casein genes and mTOR-related genes in bovine mammary epithelial cells.”

“Supplementation of casein diet with glycine, alanine, arginine and cystine tended to decrease cholesterol in the sub-fraction of LDL with larger molecular weight.”

“ Arginine increased N retention, as did CAS , compared to LAA.”

“Furthermore, this is largely prevented by addition of arginine to diets containing casein as the sole protein source.”

“Supplementation of the casein diet with arginine , to give an arginine/lysine ratio comparable to that in the soy diet, resulted in a reduction of d less than 1.006 g/ml lipids, a reduction in serum insulin levels and an elevation in hepatic 7 alpha-hydroxylase activity.”

“Furthermore, addition of arginine to the casein diet resulted in a slowed rate of lipid absorption, and addition of lysine to the soy diet markedly increased the rate of lipid absorption.”

“Growth of tumor bearing mice was significantly inhibited by feeding a purified casein diet supplemented with 5% arginine.”