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“The administration of a single dose of N-carbamyl-L-glutamate (1 mmol/kg) plus L-arginine (1 mmol/kg) 1 h before the last administration of ammonium acetate totally blocked the inhibitory effects of the latter on somatostatin receptor number in the frontoparietal cortex synaptosomes.”
“Treatment with N‐carbamyl‐L‐glutamate (1 mmol/Kg, i. p.) plus L‐arginine (1 mmol/Kg), which lead to the conversion of ammonia into urea, prevented the ammonium acetate‐induced changes in somatostatin binding in this brain area.”