Possible Interaction: Arginine and Calcium Supplement

“Mutation of an arginine (R153A) in the first intracellular loop reduced calcium , but not cAMP responses.”

“The activity of this enzyme on its substrate, arginine , is regulated by the concentration of free calcium and by intracellular phosphorylations.”

“Insulin, angiotensin II, arginine vasopressin, and norepinephrine significantly increased calcium (to 115±7, 183±20, 184±15, and 168±12 nmol/L, respectively, from basal calcium of 90±10 nmol/L).”

“Furthermore, previous studies found that both calcium and magnesium inhibit the transport of arginine.”

“When applied at low concentrations, l‐arginine (to 500 µm) and NO donors (to 50 µm) activated the respiration and increased the threshold concentrations of calcium and d,l‐palmitoylcarnitine required for the dissipation of the mitochondrial membrane potential and pore opening.”

“Calcium did not appear to protect against Cu-induced olfactory dysfunction; and even alone, Ca appeared to interfere with the olfactory response to the amino acid L-arginine.”

“It … of Ca ²⁺ to levels comparable to the … the association PC2 and IP₃ R , and increased the interaction between STIM and IP₃R. Overall, our studies … mechanism for the modulation of intracellular Ca²⁺ signaling by the polycystins.”

“ l-Arg also effectively prevents the deposition of calcium oxalate crystals by curtailing the renal epithelial damage and protein oxidation as evidenced by the normal activities of urinary marker enzymes in l-arg supplemented hyperoxaluric rats.”

“ l-arginine potentiated cadmium-induced increase of saliva calcium concentration.”

“Peptidylarginine deiminase (PAD) is a post-translational modification enzyme that catalyzes deimination of arginine residues of proteins in the presence of calcium ions.”