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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Arginine
drug:
Bradykinin
Research Papers that Mention the Interaction
“BNP and Ang II levels were similarly reduced by I and R, while bradykinin increased more with R (+132 vs +86%, p < 0.05).”
Effect of imidapril versus ramipril on urinary albumin excretion in hypertensive patients with type 2 diabetes and microalbuminuria“ L-NMMA (100 nmol·min−1) stereospecifically inhibited vasodilatation induced by acetylcholine and bradykinin (p<0.02) but not that induced by the endothelium independent vasodilator glyceryl trinitrate.”
“Coinfusion of L-arginine (0.33 mg/min) markedly improved the bradykinin-induced venodilation in smokers (52 +/- 7 to 90 +/- 9%; P < 0.01).”
“ L-NMMA (100 nmol.min-1) stereospecifically inhibited vasodilatation induced by acetylcholine and bradykinin (p less than 0.02) but not that induced by the endothelium independent vasodilator glyceryl trinitrate.”
“In addition, the arginine –silicate complex increased coronary vasodilatation in response to bradykinin.”
A novel complex of arginine–silicate improves micro- and macrovascular function and inhibits glomerular sclerosis in insulin-resistant JCR:LA-cp rats“Combining M and R individually with T resulted in a significantly larger inhibition of the bradykinin response than with each of the drugs given separately.”
“At 2 weeks, both glutathione and L-arginine significantly improved CFV after bradykinin.”
“L-NAME (20 mg kg−1) also enhanced responsiveness to bradykinin (10 μg) but only in arthritic rats, whereas l-arginine (50 mg kg−1) reduced the excitation by bradykinin (30 μg) in both groups.”
“ BK also inhibited the arginine vasopressin dependent increase of cyclic adenosine monophosphate.”
“ L-Arginine supplementation decreased bradykinin hypersensitivity but had no effect on the changes in norepinephrine serotonin and histamine responses compared to controls.”
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