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“It was unclear if dropouts due to adverse events differed (risk ratio (RR) 2.51; 95% CI 0.42 to 14.94; I² = 0%) However, BtA treatment increased the risk of experiencing an adverse event ( R ) 1.23; 95% CI 1.05 to 1.43; I² = 28%).”
The Cochrane database of systematic reviews • 2020 | View Paper
“These results indicate that i) at least one arginine residue is involved in maintaining the toxigenic structure of types … and E neurotoxins; ii) the site of nicking in type E is an arginyl bond; and iii) arginine residue is critical for at … one antigenic determinant of type A neurotoxin.”