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Discover Supplement-Drug Interactions

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Last Updated: 23 days ago

Possible Interaction: Arginine and Bosentan



Research Papers that Mention the Interaction

Recent studies in our laboratory have demonstrated that bosentan , a mixed endothelin ET(A)/ET(B) receptor antagonist, prevented the upregulation of the arginine vasopressin (AVP) V(2) receptor in the inner medullary collecting duct (IMCD) of cardiomyopathic hamsters.
Metabolism: clinical and experimental  •  2004  |  View Paper
L-arginine and bosentan further decreased SVRI (L-arginine: 34+/-2%*, p<.05; bosentan : 35+/-5%*, p<.05) and PVRI (L-arginine: 28+/-2%*, p<.05; bosentan: 33+/-7%*, p<.05) and increased CI (L-arginine: 29+/-4%*, p<.05; bosentan: 11+/-5%, NS).
Shock  •  1999  |  View Paper