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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Recent studies in our laboratory have demonstrated that bosentan , a mixed endothelin ET(A)/ET(B) receptor antagonist, prevented the upregulation of the arginine vasopressin (AVP) V(2) receptor in the inner medullary collecting duct (IMCD) of cardiomyopathic hamsters.”
Endothelin upregulates the expression of vasopressin V2 mRNA in the inner medullary collecting duct of the rat.“ L-arginine and bosentan further decreased SVRI (L-arginine: 34+/-2%*, p<.05; bosentan : 35+/-5%*, p<.05) and PVRI (L-arginine: 28+/-2%*, p<.05; bosentan: 33+/-7%*, p<.05) and increased CI (L-arginine: 29+/-4%*, p<.05; bosentan: 11+/-5%, NS).”
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