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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arginine
drug:
Antipsychotic Agents
Research Papers that Mention the Interaction
“In cytosolic preparations of rat cerebellum, the antipsychotic drugs inhibited the conversion of [3H]l-arginine into [3H]l-citrulline by NO synthase in a concentration-dependent manner.”
Inhibition of neuronal nitric oxide synthase by antipsychotic drugs“Thus, treatment … or antipsychotics could alter … pathway of arginine to yield urea or nitric oxide/nitrogen gas, increasing (if AP) or decreasing (if AD) urea or nitric oxide/nitrogen … and, secondarily, excitatory glutamic acid and/or inhibitory gamma aminobutyric acid levels via different pathways in the central nervous system.”
Influence of drug treatment with antidepressants and antipsychotics on plasma urea levels
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