supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago
supplement:
Arginine
drug:
Alendronate
Research Papers that Mention the Interaction
“ Arginine and phenazopyridine enhanced the apparent permeability of alendronate by 14- and 26-fold in the PAMPA model and 6.5- and 4.4-fold across caco-2 cell monolayers, respectively.”
“Cationic counter ions, such as arginine , phenazopyridine, hyoscine and pyridostigmine, were selected to enhance the lipophilicity and permeability of alendronate.”
“Two counter ions, phenazopyridine and arginine , substantially increased the partition coefficient of alendronate by up to 1.15 and 0.73 units, respectively, in the octanol/water system.”
An investigation into the ability of alendronate ion pairs to increase oral absorption.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback