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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Arginine
drug:
Aflibercept
Research Papers that Mention the Interaction
“We conclude that aflibercept leads to vascular dysfunction and hypertension by inhibiting CAT-1/AKT/eNOS/NO signaling, increasing ET-1, and activating NOX1/NOX4-mediated oxidative stress, which can be suppressed by supplementation of L-arg.”
The vascular endothelial growth factor trap aflibercept induces vascular dysfunction and hypertension via attenuation of eNOS/NO signaling in mice.
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