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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
drug:
Uridine Triacetate
Research Papers that Mention the Interaction
“The PP5 activity toward tau was stimulated by arachidonic acid by 30‐ to 45‐fold.”
Dephosphorylation of microtubule‐associated protein tau by protein phosphatase 5“Activation of PLC-γ by tau was enhanced in the presence of unsaturated fatty acids such as arachidonic acid , saturated fatty acids being ineffective.”
“Trivalent metal ions and polyanionic structures like heparin or arachidonic acid have been shown to induce tau aggregation.”
“ Tau preparations that do not exhibit spontaneous assembly were among those induced to polymerize by arachidonic acid.”
Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease.
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