Possible Interaction: Arachidonic Acid and Tolbutamide

“Using the scrape‐loading technique in cultured …, we show that sulfonylureas such as tolbutamide and glybenzcyclamide, which inhibit the ATP‐sensitive K+ channel, prevent the inhibition of gap junction permeability caused by several structurally unrelated uncouplers such as oleic acid, arachidonic acid , endothelin‐1, octanol, and α‐glycyrrhetinic acid.”