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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Arachidonic Acid
drug:
Ticagrelor
Research Papers that Mention the Interaction
“In these experiments, responses to AA (Fig. 1A) were found to be completely inhibited by ticagrelor at the higher two concentrations (representing ∼IC50 and IC90 for ADP-induced aggregation) without the need for aspirin.”
“ Ticagrelor and PAM, as well as aspirin, also produced complete, concentration-dependent inhibitions of platelet aggregations induced by AA (Fig. S3; log IC50 values for inhibition of aggregation to 1 mmol L−1 AA: ticagrelor, −6.88; PAM, −6.00; aspirin, −5.20).”
Antiplatelet effects of aspirin vary with level of P2Y12 receptor blockade supplied by either ticagrelor or prasugrel
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