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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
drug:
Thyroxine
Research Papers that Mention the Interaction
“Based on the data obtained a hypothesis is advanced according to which thyroxine inhibits the platelet aggregation, interfering with the release of arachidonic acid from phospholipids of platelets (thrombocytopathy A), whereas insulin--by blocking the cyclooxygenase activity (thrombocytopathy B).”
[Mechanism of the anti-aggregation action of thyroxine and insulin].“As compared to … of storage), arachidonic acid induced platelet aggregation … significantly reduced at T4 [26 U (14/54 U); p = 0.002], T5 [30 U (21/36 U); p = 0.007], T6 [… U (17/40 U); p = 0.004] and T7 [28 U (17/39 U); p < 0.001].”
“The thyroxine L-T4 ) injection to hypothyroid animals increased the hormones contents in blood serum and PtdInsP2 synthesis de novo as well as [3H]arachidonic acids incorporation into the PtdIns and PtdInsP2.”
Effects of thyroxine and 1-methyl, 2-mercaptoimidazol on phosphoinositides synthesis in rat liver
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