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Last Updated: 2 years ago

Possible Interaction: Arachidonic Acid and Tannins

supplement:

Arachidonic Acid

supplement:

Tannins

Research Papers that Mention the Interaction

At slightly higher concentrations, tannin promotes the dose-dependent release of arachidonic acid from the macrophage membranes (EC50 = 65 micrograms/mL), which could also contribute to the local inflammatory reaction.
Basic life sciences  •  1992  |  View Paper
The release of AA from EC was markedly inhibited either by scavengers of H2O2, by proteinase inhibitors, by cationic agents,by HClO, by tannic acid , and by quinacrin.
Inflammation  •  2004  |  View Paper
Both beta-glucan and tannin stimulated acyl turnover, especially arachidonic acid turnover, in these and other lipid classes by a factor of 2 or more.
Earlier work had shown that these agonists exhibit different effects on arachidonate liberation and release, and that only tannin inhibits the uptake and incorporation of exogenous arachidonic acid , suggesting inhibition of reacylation.
Biochimica et biophysica acta  •  1998  |  View Paper
In the present study, we demonstrate that condensed tannin also alters arachidonic acid (C20:4) metabolism in these cells.
American journal of respiratory cell and molecular biology  •  1992  |  View Paper