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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Arachidonic Acid and Tamoxifen

Research Papers that Mention the Interaction

Oxygenation of the intracellularly released arachidonic acid and its metabolic products may mediate some of the pharmacological actions of tamoxifen and raloxifene.
Tamoxifen has been shown to stimulate arachidonic acid release from rat liver cells.
BMC Cancer  •  2004  |  View Paper
Vitamin D3 and tamoxifen , however, not only stimulate the release of AA from cells: they amplify rather than inhibits induced COX activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology  •  2003  |  View Paper
Both nafoxidin and tamoxifen inhibited PCB-induced arachidonic acid release as well as 12-HETE and 12-HHT formation.
Biochemical pharmacology  •  2005  |  View Paper
TAM and TGF-beta1 enhanced the release of [3H]arachidonic acid ( AA ) from pre-labeled K2 cells, which was inhibited by dexamethasone (DEX).
Carcinogenesis  •  1998  |  View Paper