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Last Updated: 3 years ago
supplement:
Arachidonic Acid
Research Papers that Mention the Interaction
“ Arachidonic acid and its leukotriene metabolites have been shown to stimulate surfactant secretion by alveolar type II cells.”
Arachidonic acid and eicosapentaenoic acid stimulate type II pneumocyte surfactant secretion“ Arachidonic acid has been shown to stimulate lung surfactant secretion from alveolar epithelial type II cells.”
“ Surfactin blocked non-stimulated and calcium ionophore A23187-stimulated release of arachidonic acid from monkey kidney CV-1 cells, which contain a cytosolic 100 kDa PLA2 as the major activity, as shown in an anionic exchange DEAE-5PW high performance liquid chromatography profile and western blotting analysis.”
“ Natural surfactant (10–500 μg/ml) inhibited (up to 65%) prostaglandin E2 (PGE2) and thromboxane B2 (TxB2) production elicited by platelet‐activating factor (PAF, 10‐6 M) and arachidonic acid (5 10‐6 M) but not fMet‐Leu‐Phe (10‐7 M).”
“We conclude that arachidonic acid metabolites stimulate surfactant secretion in type II cells.”
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