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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
drug:
Phenylbutazone
Research Papers that Mention the Interaction
“We have inhibited the arachidonic acid cascade with the nonsteroidal anti-inflammatory drugs, indomethacin (5 mg/kg/day) and phenylbutazone (10mg/kg/day).”
Reduction of atherosclerosis with nonsteroidal anti-inflammatory drugs.“The high single dose (900 mg) of phenylbutazone significantly inhibited platelet aggregation to arachidonic acid at 1.5,4,7 and 12 hours following administration.”
“3 AA induced a reduction of histamine elevated perfusion pressure which was inhibited, dose‐dependently, by several non‐steroidal anti‐inflammatory agents including indomethacin, phenylbutazone , aspirin, benoxaprofen, BW755C and phenidone.”
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