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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
drug:
Nortriptyline
Research Papers that Mention the Interaction
“We have demonstrated that nortriptyline influences a decrease in cPLA₂-mediated arachidonic acid (AA) release through a mechanism that appears to involve the attenuation of both PKC and Erk1/2 kinase expression.”
Cytosolic phospholipase A₂ inhibition is involved in the protective effect of nortriptyline in primary astrocyte cultures exposed to combined oxygen-glucose deprivation.
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