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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
drug:
Nimodipine
Research Papers that Mention the Interaction
“In the presence of either omega-conotoxin GVIA or nimodipine, AA decreased current amplitude, confirming that L- and N-type currents, respectively, were inhibited.”
Arachidonic acid both inhibits and enhances whole cell calcium currents in rat sympathetic neurons.“Pretreatment of BAMC cells with nimodipine (1 µM), but not with ω‐conotoxin GVIA (1 µM), inhibited the secretion of ME and the expression of proENK mRNA induced by AA.”
“The results indicate that nimodipine (50-350 mumol/L) significantly inhibits platelet aggregation induced by ADP, AA , and ionophore A23187 in a dose dependent manner.”
“When the substrate was AA and the enzyme was supplied by pig lung microsomes, nimodipine (50-400 mumol/L) significantly reduced the generation of TXB2 and 6-keto-PGF 1 a in parallel.”
“Several different calcium entry blocking drugs had a partial inhibitory effect on the NE response, but it was noted that the dihydropyridine derivatives, nifedipine and nimodipine , also decreased the stimulatory effect of added exogenous arachidonic acid (AA).”
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