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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Arachidonic Acid
drug:
Naproxen
Research Papers that Mention the Interaction
“ Naproxen abolished platelet aggregation to arachidonic acid and suppressed serum thromboxane B2 (TXB2) by 98%, indices of COX-1 activity.”
Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen“2 The non‐steroidal anti‐inflammatory agents (NSAA) indomethacin (1–5 mg/l) and naproxen (12.5–25 mg/l) reversibly inhibited both phases of the response induced by AA.”
CORONARY VASOCONSTRICTOR AND VASODILATOR ACTIONS OF ARACHIDONIC ACID IN THE ISOLATED PERFUSED HEART OF THE RAT“ Naproxen , an inhibitor of prostaglandin synthesis in this system markedly reduces the stimulation of cyclic AMP by arachidonic acid but it does not affect the increase in cyclic AMP levels observed after the addition of prostaglandin E's, epinephrine or cholera enterotoxin.”
“ Naproxen could inhibit the contractility caused by AA.”
[An analysis of 220 cases of pregnancy termination and induced menstruation by alcoholic extract of Wikstroemia Chamaedaphne].
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