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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
drug:
Methylprednisolone
Research Papers that Mention the Interaction
“ABSTRACT: Methylprednisolone (30 mg/kg), which inhibits a number of mediators of hypoxic pulmonary vasoconstriction derived from arachidonic acid , has been found to alleviate hypoxic pulmonary vasoconstriction in adult humans and in the isolated rat lung preparation.”
“Chelation of extracellular calcium by 2 mM EGTA also blocked the TSST-…-induced sensitization of RTCs to LPS or lipid A. Inhibition of RTC arachidonic acid metabolism by methylprednisolone , indomethacin, ibuprofen, and piriprost significantly inhibited RTC necrosis induced by TSST-1 and LPS or lipid A by 33-62%.”
Enhancement of endotoxin-induced isolated renal tubular cell injury by toxic shock syndrome toxin 1.“ Methylprednisolone treatment prevented the decrease in arachidonic acid.”
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