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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Arachidonic Acid
drug:
Leukotriene D4
Research Papers that Mention the Interaction
“ Arachidonic acid release induced by LTD4 has been linked to a rapid induction of gene expression, and the propagation of the receptor binding signal is probably associated with enzymes that regulate gene expression.”
Transient activation of topoisomerase I in leukotriene D4 signal transduction in human cells.“ Leukotriene D4 increased the release of arachidonic acid primarily by activating phospholipase A2 while bradykinin activated the phospholipase C pathway.”
Differential effects of aspirin and dexamethasone on phospholipase A2 and C activities and arachidonic acid release from endothelial cells in response to bradykinin and leukotriene D4.“This arachidonic acid analog exerted a coronary vasodilator effect and significantly antagonized the coronary vasoconstrictor effect of LTD4.”
“A significant correlation was demonstrated between the ability of leukotriene C4, D4 and E4, FPL-55712 and arachidonic acid to inhibit lung [3H]leukotriene E4 and [3H]leukotriene D4 binding.”
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