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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
drug:
Ketamine
Research Papers that Mention the Interaction
“ Arachidonic acid resulted in a significant increase in … 50% effective concentration for the ketamine dose-response curve from 3.4 +/- 0.4 to 693 +/- 379 microM (P < 0.001) as well as … significant decrease in slope from 1.40 +/- 0.21 to 0.59 +/- 0.05 (P < 0.001).”
“Aristolochic acid and ketamine significantly inhibit the PLA2-mediated production of arachidonic acid in GH3 cells.”
A possible role for phospholipase A2 in the action of general anesthetics.
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